Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PSHAa1896Homologs of previously reported genes of unknown function. (93 aa)    
Predicted Functional Partners:
msrB
Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.958
PSHAa1897
Homologs of previously reported genes of unknown function.
     
 0.899
PSHAa1895
Putative orphan protein; No homology to any previously reported sequences.
       0.868
msrC
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.831
lptC
Conserved protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
    0.765
bamC
Putative lipoprotein-34 NlpB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.763
PSHAa1336
Homologs of previously reported genes of unknown function; membrane component.
  
     0.759
PSHAa1021
Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family.
  
     0.746
yihI
Conserved protein of unknown function; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.743
metJ
Transcriptional repressor for methionine biosynthesis (MetJ family); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
  
     0.738
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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