STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metCCystathionine beta-lyase, PLP-dependent (beta-cystathionase); Function of strongly homologous gene; enzyme. (393 aa)    
Predicted Functional Partners:
cysK
O-acetylserine sulfhydrylase, PLP-dependent enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 0.974
PSHAa2222
Putative B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (C terminal); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.968
PSHAa2223
putativeB12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (N terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
  
 
 0.968
sseA
Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 
 0.958
metE
5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Function of strongly homologous gene; enzyme.
  
 
 0.952
PSHAb0477
Putative cystathionine gamma-synthase or beta-lyase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 
0.940
thrA
Bifunctional aspartokinase/homoserine dehydrogenase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 
 0.931
metL
Bifunctional: aspartokinase II (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 
 0.931
metB
Cystathionine gamma-synthase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 
0.927
aspC
Aspartate aminotransferase (Transaminase A) (ASPAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.909
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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