Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa1926Putative NTP pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the Nudix hydrolase family. (307 aa)    
Predicted Functional Partners:
surE
Acid phosphatase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
 
  0.911
mazG
Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme.
     
 0.906
PSHAb0168
Putative sirtuin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
  0.906
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-requiring; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.905
PSHAa2167
Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
  0.905
ushA
Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family.
    
  0.905
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.904
PSHAa0693
Homologs of previously reported genes of unknown function; Belongs to the CinA family.
     
 0.903
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.901
nadC
Nicotinate-nucleotide pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.
     
  0.900
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (12%) [HD]