Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PSHAa1940Homologs of previously reported genes of unknown function. (166 aa)    
Predicted Functional Partners:
mazG
Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme.
    
  0.902
udk
Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.902
PSHAa2167
Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
  0.901
ushA
Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family.
  
 
  0.901
surE
Acid phosphatase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
  0.900
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
     
  0.900
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.900
PSHAa2497
Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
  0.900
PSHAa2679
Conserved protein of unknown function with Maf/Ham1 domain; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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