node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAa0027 | rnhA | PSHAa0027 | PSHAa1964 | Putative DNA topoisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.497 |
PSHAa0027 | ssb | PSHAa0027 | PSHAa2705 | Putative DNA topoisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.729 |
PSHAa0027 | topA | PSHAa0027 | PSHAa1348 | Putative DNA topoisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...] | 0.509 |
PSHAa1962 | dnaQ | PSHAa1962 | PSHAa1963 | Homologs of previously reported genes of unknown function. | DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.800 |
PSHAa1962 | rnhA | PSHAa1962 | PSHAa1964 | Homologs of previously reported genes of unknown function. | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.595 |
PSHAa1965 | rnhA | PSHAa1965 | PSHAa1964 | Homologs of previously reported genes of unknown function. | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.640 |
PSHAb0257 | rnhA | PSHAb0257 | PSHAa1964 | Putative oxidoreductase/dehydrogenase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.635 |
dnaQ | PSHAa1962 | PSHAa1963 | PSHAa1962 | DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Homologs of previously reported genes of unknown function. | 0.800 |
dnaQ | rnhA | PSHAa1963 | PSHAa1964 | DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.984 |
dnaQ | ssb | PSHAa1963 | PSHAa2705 | DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.551 |
rnc | rnhA | PSHAa0732 | PSHAa1964 | RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.508 |
rnc | rnhB | PSHAa0732 | PSHAa2016 | RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.515 |
rnhA | PSHAa0027 | PSHAa1964 | PSHAa0027 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Putative DNA topoisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.497 |
rnhA | PSHAa1962 | PSHAa1964 | PSHAa1962 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Homologs of previously reported genes of unknown function. | 0.595 |
rnhA | PSHAa1965 | PSHAa1964 | PSHAa1965 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Homologs of previously reported genes of unknown function. | 0.640 |
rnhA | PSHAb0257 | PSHAa1964 | PSHAb0257 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Putative oxidoreductase/dehydrogenase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.635 |
rnhA | dnaQ | PSHAa1964 | PSHAa1963 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.984 |
rnhA | rnc | PSHAa1964 | PSHAa0732 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.508 |
rnhA | rnhB | PSHAa1964 | PSHAa2016 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.829 |
rnhA | ssb | PSHAa1964 | PSHAa2705 | RNase HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.761 |