STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloBPutative hydroxyacylglutathione hydrolase with metallo-hydrolase/oxidoreductase domain; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (257 aa)    
Predicted Functional Partners:
gloA
Glyoxalase I, nickel isomerase (Lactoylglutathione lyase); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
  
 0.986
gloA-2
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
  
 0.983
PSHAa1401
Putative enzyme with metallo-hydrolase/oxidoreductase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
  
0.918
PSHAa1965
Homologs of previously reported genes of unknown function.
     
 0.817
mltD-2
Lytic murein transglycosylase C, membrane-bound; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.771
PSHAa1216
Conserved protein of unknown function with thioredoxin-like domain; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily.
 
  
 0.524
gshB
Glutathione synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic GSH synthase family.
 
   
 0.508
grxA
Glutaredoxin 1 redox coenzyme for glutathione-dependent ribonucleotide reductase; Function of homologous gene experimentally demonstrated in an other organism; carrier.
      
 0.418
guaB
IMP dehydrogeanse; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.417
gor
Glutathione reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.416
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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