| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa0897 | accC | PSHAa0897 | PSHAa0266 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.680 |
| PSHAa0897 | aceF | PSHAa0897 | PSHAa0392 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.906 |
| PSHAa0897 | acs | PSHAa0897 | PSHAa0698 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.930 |
| PSHAa0897 | glcB | PSHAa0897 | PSHAb0061 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.922 |
| PSHAa0897 | sucB | PSHAa0897 | PSHAa1646 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | Dihydrolipoyltranssuccinate transferase, component of the 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.812 |
| PSHAa0897 | sucC | PSHAa0897 | PSHAa1645 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.820 |
| PSHAa0897 | sucD | PSHAa0897 | PSHAa1644 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.827 |
| PSHAa0897 | ygfH | PSHAa0897 | PSHAa2002 | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | propionyl-CoA:succinate-CoA transferase; Function of strongly homologous gene; enzyme. | 0.908 |
| accC | PSHAa0897 | PSHAa0266 | PSHAa0897 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | 0.680 |
| accC | aceF | PSHAa0266 | PSHAa0392 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.909 |
| accC | acs | PSHAa0266 | PSHAa0698 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.920 |
| accC | glcB | PSHAa0266 | PSHAb0061 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.905 |
| accC | sucC | PSHAa0266 | PSHAa1645 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.850 |
| accC | sucD | PSHAa0266 | PSHAa1644 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.810 |
| accC | ygfH | PSHAa0266 | PSHAa2002 | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | propionyl-CoA:succinate-CoA transferase; Function of strongly homologous gene; enzyme. | 0.923 |
| aceF | PSHAa0897 | PSHAa0392 | PSHAa0897 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Putative nonspecific lipid-transfer protein; Homologs of previously reported genes of unknown function. | 0.906 |
| aceF | accC | PSHAa0392 | PSHAa0266 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Biotin carboxylase (A subunit of acetyl-CoA carboxylase)(ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.909 |
| aceF | acs | PSHAa0392 | PSHAa0698 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.907 |
| aceF | glcB | PSHAa0392 | PSHAb0061 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.908 |
| aceF | sdhA | PSHAa0392 | PSHAa1649 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.487 |