STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaEDNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1163 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.998
holA
Putative DNA polymerase III, delta subunit, probably ATP hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 0.998
holB
Putative DNA polymerase III delta' subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 0.997
PSHAa1201
Putative DnaX, DNA polymerase III, gamma/tau subunits; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 0.996
holC
DNA polymerase III, chi subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.996
dnaQ
DNA polymerase III: epsilon subunit, 3-5 exonucleolytic proofreading function; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
   
 0.994
ssb
Single-strand binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 
 0.976
accA
acetylCoA carboxylase, carboxytransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
    0.960
PSHAa0589
Putative DNA polymerase, exonuclease activity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 0.947
PSHAa1435
Putative DNA polymerase III, epsilon subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.946
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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