Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phhAPhenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4-monooxygenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (265 aa)    
Predicted Functional Partners:
phhB
Pterin-4-alpha-carbinolamine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
hisC
Histidinol phosphate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.968
aspC
Aspartate aminotransferase (Transaminase A) (ASPAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.959
melA
4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.950
pheA
Bifunctional protein [Includes: chorismate mutase P (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.930
hmgA
Homogentisate 1,2-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.930
folA
Dihydrofolate reductase type I, trimethoprim resistance; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.904
maiA
Maleylacetoacetate isomerase (MAAI) (Glutathione S-transferase zeta 1) (GSTZ1-1); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.811
ubiC
Putative chorismate pyruvate lyase UbiC; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
     
  0.800
mdeA
Probable Methionine gamma-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.720
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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