Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa2069Putative orphan protein; No homology to any previously reported sequences. (199 aa)    
Predicted Functional Partners:
PSHAa2068
TRNA-(MS[2]IO[6]A)-hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.733
rsd
Stationary-phase regulator of sigma D, the major sigma subunit of RNA polymerase; Function of strongly homologous gene; regulator; Belongs to the Rsd/AlgQ family.
  
     0.660
mshD
Putative Mannose-sensitive agglutinin (MSHA) biogenesis protein MshD (pilus type IV); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; 11985966.
  
     0.618
mshB
Putative Mannose-sensitive agglutinin (MSHA) biogenesis protein MshB (pilus type IV); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; 11985966.
  
     0.611
seqA
SeqA protein, recognizes hemimethylated GATC motifs; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.568
PSHAa1212
Homologs of previously reported genes of unknown function.
   
    0.565
PSHAa1971
Homologs of previously reported genes of unknown function.
  
     0.541
PSHAa2699
MSHA biogenesis protein MshI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; 11985966.
  
     0.534
PSHAa0455
Homologs of previously reported genes of unknown function.
  
     0.532
PSHAa1817
Putative nucleotide associated protein, present in spermidine nucleoids; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; structural protein.
  
     0.527
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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