STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hdhA7-alpha-hydroxysteroid dehydrogenase (7-alpha-HSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (264 aa)    
Predicted Functional Partners:
hsdA
3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.775
bdhA
Putative 3-hydroxybutyrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.746
PSHAa2128
Putative acetyl-CoA acetyltransferase or Thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 
   0.630
fabD
malonyl-CoA-[acyl-carrier-protein] transacylase; Function of strongly homologous gene; enzyme.
 
 0.587
PSHAa0886
Homologs of previously reported genes of unknown function.
 
 0.456
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.445
PSHAa0291
Putative glucose/ribitol dehydrogenase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
    
0.442
PSHAa1861
Putative orphan protein; No homology to any previously reported sequences.
   
 
 0.442
PSHAa2198
Putative orphan protein; No homology to any previously reported sequences.
   
 
 0.442
PSHAb0407
Putative 3-oxoacyl-(Acyl-carrier-protein) synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.434
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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