Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xylJ2-hydroxypent-2,4-dienoate hydratase (HPH) (2-oxopent-4-enoate hydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (262 aa)    
Predicted Functional Partners:
mhpE
4-hydroxy-2-oxovalerate aldolase (HOA); Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.994
mhpF
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.991
tesD
Putative hydrolase acting on oxygenated substrates (epoxide hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.979
tesA
TesA protein; Function of strongly homologous gene.
 
  
 0.848
tesB-2
Putative dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.605
PSHAa0329
Putative 5-carboxymethyl-2-hydroxymuconate delta isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
  
 0.602
PSHAa2144
Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
  
    0.516
PSHAa0877
Putative steroid degradation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
   
 0.453
hsdA
3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.405
PSHAa1473
Putative orphan protein; No homology to any previously reported sequences.
  
  
 0.401
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.