STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa2151Putative reductase or dehydrogenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (261 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.933
fabB
3-oxoacyl-[acyl-carrier-protein] synthase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.933
PSHAb0407
Putative 3-oxoacyl-(Acyl-carrier-protein) synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.933
PSHAb0410
Putative 3-oxoacyl-[acyl-carrier-protein] synthase II (fabF-like); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.933
fabA
Beta-hydroxydecanoyl thioester dehydrase (trans-2-decenoyl-ACP isomerase); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 0.930
PSHAa0909
Putative 3-oxoacyl-[acyl-carrier protein] reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    
0.927
fabZ
(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 0.924
fabH
3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.912
PSHAa2150
Homologs of previously reported genes of unknown function; enzyme.
 
 0.839
PSHAa0886
Homologs of previously reported genes of unknown function.
 
 0.802
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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