Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
faHFumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase)(FAA); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (437 aa)    
Predicted Functional Partners:
maiA
Maleylacetoacetate isomerase (MAAI) (Glutathione S-transferase zeta 1) (GSTZ1-1); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.995
hmgA
Homogentisate 1,2-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.985
melA
4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.973
fumC
Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.819
sdhA
Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.812
sdhB
Succinate dehydrogenase, Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
  0.811
sdhD
Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhC; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
 
  0.806
sdhC
Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 
  0.804
fumB
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.802
PSHAa2170
Putative peptidase family M23/M37 protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.735
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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