Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa2177Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (280 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.934
polA
Multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.926
PSHAa1990
DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.779
PSHAa2176
Putative heat shock protein (Hsp70 family), actin-like ATPase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
   
   0.742
xni
Putative exonuclease IX, 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
  
 0.708
holB
Putative DNA polymerase III delta' subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.694
xthA
Exonuclease III; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.691
PSHAa2178
Putative enzymatic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.688
PSHAa2179
Putative orphan protein; No homology to any previously reported sequences.
       0.600
cpsB
Putative mannose-1-phosphate guanyltransferase, colanic acid synthesis; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
     0.549
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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