Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa2252Putative Voltage-gated ClC-type chloride channel clcA; Function of homologous gene experimentally demonstrated in an other organism; transporter. (560 aa)    
Predicted Functional Partners:
PSHAa2253
Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
  
    0.872
pyrB
Aspartate transcarbamoylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
     0.783
erpA
Putative HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
       0.702
hemL
Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (Glutamate-1-semialdehyde aminotransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.700
PSHAa0548
Homologs of previously reported genes of unknown function.
  
    0.492
thiDE
Putative phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.461
dagA
Na(+)-linked D-alanine glycine permease; Function of homologous gene experimentally demonstrated in an other organism; transporter.
   
    0.453
PSHAa1913
Putative sodium:alanine symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
   
    0.453
yaaJ
Putative amino acid permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
   
    0.453
putA
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
   
 0.404
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.