| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa0522 | dacA | PSHAa0522 | PSHAa1022 | Homologs of previously reported genes of unknown function. | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | 0.927 |
| PSHAa0522 | ftsI | PSHAa0522 | PSHAa2510 | Homologs of previously reported genes of unknown function. | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.928 |
| PSHAa0522 | mrcA | PSHAa0522 | PSHAa2721 | Homologs of previously reported genes of unknown function. | Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.926 |
| PSHAa0522 | mrcB | PSHAa0522 | PSHAa2256 | Homologs of previously reported genes of unknown function. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.929 |
| PSHAa0522 | mrdA | PSHAa0522 | PSHAa1025 | Homologs of previously reported genes of unknown function. | Cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.928 |
| PSHAa2257 | mrcB | PSHAa2257 | PSHAa2256 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.671 |
| PSHAa2729 | ftsI | PSHAa2729 | PSHAa2510 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.914 |
| PSHAa2729 | ftsW | PSHAa2729 | PSHAa2505 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.890 |
| PSHAa2729 | mrcB | PSHAa2729 | PSHAa2256 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.914 |
| PSHAa2729 | mrdA | PSHAa2729 | PSHAa1025 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.513 |
| PSHAa2729 | mrdB | PSHAa2729 | PSHAa1024 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Rod shape-determining membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.492 |
| dacA | PSHAa0522 | PSHAa1022 | PSHAa0522 | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | Homologs of previously reported genes of unknown function. | 0.927 |
| dacA | ftsI | PSHAa1022 | PSHAa2510 | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.945 |
| dacA | mrcA | PSHAa1022 | PSHAa2721 | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.929 |
| dacA | mrcB | PSHAa1022 | PSHAa2256 | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.937 |
| dacA | mrdA | PSHAa1022 | PSHAa1025 | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | Cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.997 |
| dacA | mrdB | PSHAa1022 | PSHAa1024 | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | Rod shape-determining membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.784 |
| ftsI | PSHAa0522 | PSHAa2510 | PSHAa0522 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Homologs of previously reported genes of unknown function. | 0.928 |
| ftsI | PSHAa2729 | PSHAa2510 | PSHAa2729 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | 0.914 |
| ftsI | dacA | PSHAa2510 | PSHAa1022 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S11 family. | 0.945 |