| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa0751 | mrcB | PSHAa0751 | PSHAa2256 | Putative orphan protein; No homology to any previously reported sequences. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.704 |
| PSHAa1325 | mrcB | PSHAa1325 | PSHAa2256 | Homologs of previously reported genes of unknown function. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.745 |
| PSHAa2257 | glnA | PSHAa2257 | PSHAa0166 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.539 |
| PSHAa2257 | glnK | PSHAa2257 | PSHAa2258 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.999 |
| PSHAa2257 | mrcB | PSHAa2257 | PSHAa2256 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.726 |
| PSHAa2729 | ftsI | PSHAa2729 | PSHAa2510 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.775 |
| PSHAa2729 | mrcB | PSHAa2729 | PSHAa2256 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.868 |
| PSHAa2729 | mrdB | PSHAa2729 | PSHAa1024 | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | Rod shape-determining membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.414 |
| ftsI | PSHAa2729 | PSHAa2510 | PSHAa2729 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Conserved protein of unknown function, putative cell division protein; Homologs of previously reported genes of unknown function. | 0.775 |
| ftsI | mrcA | PSHAa2510 | PSHAa2721 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.694 |
| ftsI | mrcB | PSHAa2510 | PSHAa2256 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.817 |
| ftsI | mrdA | PSHAa2510 | PSHAa1025 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.940 |
| ftsI | mrdB | PSHAa2510 | PSHAa1024 | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Rod shape-determining membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.946 |
| glnA | PSHAa2257 | PSHAa0166 | PSHAa2257 | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.539 |
| glnA | glnK | PSHAa0166 | PSHAa2258 | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.464 |
| glnA | mrcB | PSHAa0166 | PSHAa2256 | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.662 |
| glnK | PSHAa2257 | PSHAa2258 | PSHAa2257 | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.999 |
| glnK | glnA | PSHAa2258 | PSHAa0166 | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.464 |
| glnK | mrcB | PSHAa2258 | PSHAa2256 | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.660 |
| mrcA | ftsI | PSHAa2721 | PSHAa2510 | Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Division-specific transpeptidase, penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.694 |