| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa2257 | PSHAa2259 | PSHAa2257 | PSHAa2259 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Putative two-component response regulator protein with GGDEF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | 0.476 |
| PSHAa2257 | glnA | PSHAa2257 | PSHAa0166 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.681 |
| PSHAa2257 | glnD | PSHAa2257 | PSHAa2038 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.534 |
| PSHAa2257 | glnK | PSHAa2257 | PSHAa2258 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.999 |
| PSHAa2257 | glnL | PSHAa2257 | PSHAa0164 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL; Function of homologous gene experimentally demonstrated in an other organism; regulator. | 0.796 |
| PSHAa2257 | gltB | PSHAa2257 | PSHAb0127 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.881 |
| PSHAa2257 | mrcB | PSHAa2257 | PSHAa2256 | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | Murein polymerase, bifunctional murein transglycosylase and transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.671 |
| PSHAa2259 | PSHAa2257 | PSHAa2259 | PSHAa2257 | Putative two-component response regulator protein with GGDEF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.476 |
| PSHAa2259 | PSHAa2767 | PSHAa2259 | PSHAa2767 | Putative two-component response regulator protein with GGDEF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | Homologs of previously reported genes of unknown function. | 0.689 |
| PSHAa2259 | glnK | PSHAa2259 | PSHAa2258 | Putative two-component response regulator protein with GGDEF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.455 |
| PSHAa2767 | PSHAa2259 | PSHAa2767 | PSHAa2259 | Homologs of previously reported genes of unknown function. | Putative two-component response regulator protein with GGDEF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator. | 0.689 |
| PSHAa2767 | glnA | PSHAa2767 | PSHAa0166 | Homologs of previously reported genes of unknown function. | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.494 |
| PSHAa2767 | glnK | PSHAa2767 | PSHAa2258 | Homologs of previously reported genes of unknown function. | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.666 |
| PSHAa2767 | gltB | PSHAa2767 | PSHAb0127 | Homologs of previously reported genes of unknown function. | Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.637 |
| argB | glnK | PSHAa2290 | PSHAa2258 | Acetylglutamate kinase (NAG kinase) (AGK) (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. | 0.797 |
| argB | gltB | PSHAa2290 | PSHAb0127 | Acetylglutamate kinase (NAG kinase) (AGK) (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.784 |
| argB | purL | PSHAa2290 | PSHAa2330 | Acetylglutamate kinase (NAG kinase) (AGK) (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Phophoribosylformylglycinamidine synthase (FGAM synthetase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.588 |
| glnA | PSHAa2257 | PSHAa0166 | PSHAa2257 | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Ammonium/methylammonium transporter amtB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.681 |
| glnA | PSHAa2767 | PSHAa0166 | PSHAa2767 | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Homologs of previously reported genes of unknown function. | 0.494 |
| glnA | glnD | PSHAa0166 | PSHAa2038 | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.634 |