Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
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putADelta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1267 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase (NAD(P)-binding); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.975
PSHAb0543
Putative ornithine cyclodeaminase; Function of strongly homologous gene; enzyme.
 
 
 0.974
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.956
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.956
gltB
Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.949
proB
Putative glutamate 5-kinase (Gamma-glutamyl kinase); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.945
proB-2
Glutamate-5 kinase(Gamma-glutamyl kinase)(GK); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.945
gdhA
Glutamate dehydrogenase, NADP-specific; Function of strongly homologous gene; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.944
PSHAa1670
Putative glutamate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
  
 0.924
putP
Major sodium/proline symporter (SSS family); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.920
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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