Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrABprotein-methionine-S-oxide reductase (Peptide Met(O) reductase); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (178 aa)    
Predicted Functional Partners:
msrB
Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.986
PSHAa2272
Homologs of previously reported genes of unknown function; membrane component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.764
PSHAa2273
Putative acrB/acrD/acrF acriflavin resistance family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.764
argF
Ornithine carbamoyltransferase (OTCase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
   0.681
PSHAa1681
Homologs of previously reported genes of unknown function.
 
    
 0.637
PSHAa2223
putativeB12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (N terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
  
  
 0.605
PSHAa2271
Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
       0.595
PSHAa2222
Putative B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (C terminal); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.574
PSHAa2270
Putative orphan protein; No homology to any previously reported sequences.
       0.549
msrC
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
0.512
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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