| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1693 | PSHAa2309 | PSHAa1693 | PSHAa2309 | Putative enzyme with RmlC-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.435 |
| PSHAa1932 | PSHAa2309 | PSHAa1932 | PSHAa2309 | Isopenicillin N synthase; Function of strongly homologous gene; enzyme; Belongs to the iron/ascorbate-dependent oxidoreductase family. | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.540 |
| PSHAa2308 | PSHAa2309 | PSHAa2308 | PSHAa2309 | Putative transcriptional regulator, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the LysR transcriptional regulatory family. | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.714 |
| PSHAa2309 | PSHAa1693 | PSHAa2309 | PSHAa1693 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative enzyme with RmlC-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.435 |
| PSHAa2309 | PSHAa1932 | PSHAa2309 | PSHAa1932 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Isopenicillin N synthase; Function of strongly homologous gene; enzyme; Belongs to the iron/ascorbate-dependent oxidoreductase family. | 0.540 |
| PSHAa2309 | PSHAa2308 | PSHAa2309 | PSHAa2308 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative transcriptional regulator, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator; Belongs to the LysR transcriptional regulatory family. | 0.714 |
| PSHAa2309 | hemF | PSHAa2309 | PSHAa0029 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.524 |
| PSHAa2309 | pyrG | PSHAa2309 | PSHAa0741 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.445 |
| PSHAa2309 | rpsL | PSHAa2309 | PSHAa0224 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.698 |
| PSHAa2309 | tmcA | PSHAa2309 | PSHAa0121 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Conserved protein of unknown function; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.511 |
| PSHAa2309 | tufA | PSHAa2309 | PSHAa0227 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.572 |
| PSHAa2309 | tufB | PSHAa2309 | PSHAa2911 | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.572 |
| hemF | PSHAa2309 | PSHAa0029 | PSHAa2309 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.524 |
| pyrG | PSHAa2309 | PSHAa0741 | PSHAa2309 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.445 |
| pyrG | rpsL | PSHAa0741 | PSHAa0224 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.430 |
| pyrG | tmcA | PSHAa0741 | PSHAa0121 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Conserved protein of unknown function; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.514 |
| rpsL | PSHAa2309 | PSHAa0224 | PSHAa2309 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | Putative prolyl 4-hydroxylase, alpha subunit domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.698 |
| rpsL | pyrG | PSHAa0224 | PSHAa0741 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.430 |
| rpsL | tmcA | PSHAa0224 | PSHAa0121 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | Conserved protein of unknown function; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.782 |
| rpsL | tufA | PSHAa0224 | PSHAa0227 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.988 |