node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAa2318 | PSHAa2324 | PSHAa2318 | PSHAa2324 | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.728 |
PSHAa2318 | gmhB | PSHAa2318 | PSHAa2317 | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Heptose 1,7-bisphosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.975 |
PSHAa2318 | kdtA | PSHAa2318 | PSHAa2325 | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.928 |
PSHAa2318 | ksdD | PSHAa2318 | PSHAa2546 | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | D-arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.560 |
PSHAa2318 | rfaE | PSHAa2318 | PSHAa2323 | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Bifunctional ADP-L-glycero-D-manno-heptose synthase: putaive kinase (N-terminal); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.836 |
PSHAa2324 | PSHAa2318 | PSHAa2324 | PSHAa2318 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.728 |
PSHAa2324 | PSHAa2326 | PSHAa2324 | PSHAa2326 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Homologs of previously reported genes of unknown function. | 0.526 |
PSHAa2324 | dnaA | PSHAa2324 | PSHAa0001 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | DNA replication initiator protein, transcriptional regulator of replication and other genes; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.502 |
PSHAa2324 | gmhB | PSHAa2324 | PSHAa2317 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Heptose 1,7-bisphosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.991 |
PSHAa2324 | hisB | PSHAa2324 | PSHAb0491 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Modular bifunctional: histidinol-phosphatase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.761 |
PSHAa2324 | kdtA | PSHAa2324 | PSHAa2325 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.586 |
PSHAa2324 | ksdD | PSHAa2324 | PSHAa2546 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | D-arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.448 |
PSHAa2324 | rfaE | PSHAa2324 | PSHAa2323 | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Bifunctional ADP-L-glycero-D-manno-heptose synthase: putaive kinase (N-terminal); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.999 |
PSHAa2326 | PSHAa2324 | PSHAa2326 | PSHAa2324 | Homologs of previously reported genes of unknown function. | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.526 |
PSHAa2326 | kdtA | PSHAa2326 | PSHAa2325 | Homologs of previously reported genes of unknown function. | Putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.800 |
PSHAa2326 | rfaE | PSHAa2326 | PSHAa2323 | Homologs of previously reported genes of unknown function. | Bifunctional ADP-L-glycero-D-manno-heptose synthase: putaive kinase (N-terminal); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.520 |
dnaA | PSHAa2324 | PSHAa0001 | PSHAa2324 | DNA replication initiator protein, transcriptional regulator of replication and other genes; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.502 |
gmhB | PSHAa2318 | PSHAa2317 | PSHAa2318 | Heptose 1,7-bisphosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative ADP-heptose:LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.975 |
gmhB | PSHAa2324 | PSHAa2317 | PSHAa2324 | Heptose 1,7-bisphosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative phosphoheptose isomerase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.991 |
gmhB | rfaE | PSHAa2317 | PSHAa2323 | Heptose 1,7-bisphosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Bifunctional ADP-L-glycero-D-manno-heptose synthase: putaive kinase (N-terminal); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.984 |