Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
topBDNA topoisomerase III; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (629 aa)    
Predicted Functional Partners:
PSHAa0027
Putative DNA topoisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 0.847
recQ
ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.822
sbcC
Exonuclease sbcCD subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 0.805
PSHAb0119
Putative helicase (recQ-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 0.728
PSHAa2360
Putative phage integrase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
 0.651
PSHAa2357
Putative orphan protein; No homology to any previously reported sequences.
       0.625
PSHAa2358
Putative orphan protein; No homology to any previously reported sequences.
       0.625
PSHAa2359
Putative phage integrase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.625
PSHAa2361
DNA topoisomerase III (N terminal part); Gene remnant; enzyme.
 
    
0.563
recA
RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.551
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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