| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dxs | ispA | PSHAa2366 | PSHAa2365 | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.966 |
| dxs | ispH | PSHAa2366 | PSHAa0921 | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.871 |
| dxs | motA | PSHAa2366 | PSHAa2363 | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Flagellar motor component (Chemotaxis motA protein); Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.623 |
| dxs | motB-2 | PSHAa2366 | PSHAa2362 | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Sodium-driven polar flagellar protein; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.623 |
| dxs | thiL | PSHAa2366 | PSHAa2369 | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.517 |
| dxs | xseB | PSHAa2366 | PSHAa2364 | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.800 |
| ispA | dxs | PSHAa2365 | PSHAa2366 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase); Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.966 |
| ispA | ispB | PSHAa2365 | PSHAa2657 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase)(OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.927 |
| ispA | ispH | PSHAa2365 | PSHAa0921 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.936 |
| ispA | ispU | PSHAa2365 | PSHAa2032 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.971 |
| ispA | motA | PSHAa2365 | PSHAa2363 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Flagellar motor component (Chemotaxis motA protein); Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.669 |
| ispA | motB-2 | PSHAa2365 | PSHAa2362 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Sodium-driven polar flagellar protein; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.675 |
| ispA | rplO | PSHAa2365 | PSHAa2811 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.510 |
| ispA | thiL | PSHAa2365 | PSHAa2369 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.590 |
| ispA | xseA | PSHAa2365 | PSHAa0647 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.585 |
| ispA | xseB | PSHAa2365 | PSHAa2364 | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.937 |
| ispB | ispA | PSHAa2657 | PSHAa2365 | Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase)(OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 0.927 |
| ispB | ispU | PSHAa2657 | PSHAa2032 | Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase)(OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.977 |
| ispB | rplO | PSHAa2657 | PSHAa2811 | Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase)(OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.510 |
| ispB | xseA | PSHAa2657 | PSHAa0647 | Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase)(OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.488 |