Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (311 aa)    
Predicted Functional Partners:
thrC
Threonine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
thrA
Bifunctional aspartokinase/homoserine dehydrogenase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.999
metL
Bifunctional: aspartokinase II (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.999
metA
Homoserine O-succinyltransferase (Homoserine O-transsuccinylase) (HTS); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
    
 0.913
metX
Putative homoserine O-acetyltransferase (EC 2.3. 1.31); Function of strongly homologous gene; enzyme; Belongs to the AB hydrolase superfamily. MetX family.
     
 0.911
lysC-2
Lysine-sensitive aspartokinase III; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
 
 
 0.909
PSHAa2222
Putative B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (C terminal); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.876
PSHAa2223
putativeB12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (N terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
    
 0.876
metB
Cystathionine gamma-synthase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.864
ilvE
Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 0.833
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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