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dinB protein (Pseudoalteromonas haloplanktis TAC125) - STRING interaction network
"dinB" - DNA polymerase IV in Pseudoalteromonas haloplanktis TAC125
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3’-5’ exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (351 aa)    
Predicted Functional Partners:
dnaN
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (367 aa)
     
 
  0.956
lexA
Transcriptional repressor for SOS response; Represses a number of genes involved in the response to DNA damage (SOS response) (182 aa)
   
 
  0.820
umuD
Component of DNA polymerase V; Evidence 2b - Function of strongly homologous gene; Product type e - enzyme (137 aa)
   
 
  0.819
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (347 aa)
   
 
  0.781
PSHAa1990
DNA polymerase; Evidence 2a - Function of homologous gene experimentally demonstrated in an other organism; Product type e - enzyme (806 aa)
     
 
  0.743
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (911 aa)
   
 
  0.731
recX
Regulatory protein RecX; Modulates RecA activity (150 aa)
     
   
  0.643
PSHAa2390
Putative membrane protein; Evidence 3 - Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; Product type m - membrane component (58 aa)
              0.625
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA (557 aa)
   
   
  0.587
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (618 aa)
   
 
  0.550
Your Current Organism:
Pseudoalteromonas haloplanktis TAC125
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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