| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa2167 | PSHAa2497 | PSHAa2167 | PSHAa2497 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.923 |
| PSHAa2167 | cdd | PSHAa2167 | PSHAb0315 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.908 |
| PSHAa2167 | surE | PSHAa2167 | PSHAa0687 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Acid phosphatase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.911 |
| PSHAa2167 | tdk | PSHAa2167 | PSHAb0294 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.922 |
| PSHAa2167 | thyA | PSHAa2167 | PSHAa0749 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.905 |
| PSHAa2167 | tmk | PSHAa2167 | PSHAa1803 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.917 |
| PSHAa2167 | udk | PSHAa2167 | PSHAb0080 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.904 |
| PSHAa2167 | udp | PSHAa2167 | PSHAb0316 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.902 |
| PSHAa2167 | upp | PSHAa2167 | PSHAb0377 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Uracil phosphoribosyltransferase (UMP pyrophosphorylase) (UPRTase); Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.906 |
| PSHAa2167 | ushA | PSHAa2167 | PSHAb0345 | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family. | 0.949 |
| PSHAa2497 | PSHAa2167 | PSHAa2497 | PSHAa2167 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.923 |
| PSHAa2497 | cdd | PSHAa2497 | PSHAb0315 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.903 |
| PSHAa2497 | surE | PSHAa2497 | PSHAa0687 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Acid phosphatase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.956 |
| PSHAa2497 | tdk | PSHAa2497 | PSHAb0294 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.938 |
| PSHAa2497 | thyA | PSHAa2497 | PSHAa0749 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.904 |
| PSHAa2497 | tmk | PSHAa2497 | PSHAa1803 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.904 |
| PSHAa2497 | udk | PSHAa2497 | PSHAb0080 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.922 |
| PSHAa2497 | udp | PSHAa2497 | PSHAb0316 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.906 |
| PSHAa2497 | upp | PSHAa2497 | PSHAb0377 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Uracil phosphoribosyltransferase (UMP pyrophosphorylase) (UPRTase); Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.903 |
| PSHAa2497 | ushA | PSHAa2497 | PSHAb0345 | Putative enzyme with a phosphatase-like domain, HAD-superfamily hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Protein ushA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 5'-nucleotidase family. | 0.932 |