| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1021 | PSHAa1336 | PSHAa1021 | PSHAa1336 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Homologs of previously reported genes of unknown function; membrane component. | 0.770 |
| PSHAa1021 | PSHAa1819 | PSHAa1021 | PSHAa1819 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Homologs of previously reported genes of unknown function. | 0.754 |
| PSHAa1021 | lptC | PSHAa1021 | PSHAa2548 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Conserved protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.790 |
| PSHAa1021 | nlpI | PSHAa1021 | PSHAa1002 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Lipoprotein probably involved in cell division after interaction with a protease; May be involved in cell division. | 0.761 |
| PSHAa1021 | proQ | PSHAa1021 | PSHAa1679 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Putative post-translational activator of ProP expression; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.758 |
| PSHAa1021 | rraB-2 | PSHAa1021 | PSHAa2583 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Conserved protein of unknown function; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.774 |
| PSHAa1021 | rseA | PSHAa1021 | PSHAa0727 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Putative anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), wh [...] | 0.763 |
| PSHAa1021 | yihI | PSHAa1021 | PSHAa2751 | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | Conserved protein of unknown function; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.771 |
| PSHAa1336 | PSHAa1021 | PSHAa1336 | PSHAa1021 | Homologs of previously reported genes of unknown function; membrane component. | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | 0.770 |
| PSHAa1336 | PSHAa1819 | PSHAa1336 | PSHAa1819 | Homologs of previously reported genes of unknown function; membrane component. | Homologs of previously reported genes of unknown function. | 0.765 |
| PSHAa1336 | lptC | PSHAa1336 | PSHAa2548 | Homologs of previously reported genes of unknown function; membrane component. | Conserved protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.771 |
| PSHAa1336 | nlpI | PSHAa1336 | PSHAa1002 | Homologs of previously reported genes of unknown function; membrane component. | Lipoprotein probably involved in cell division after interaction with a protease; May be involved in cell division. | 0.752 |
| PSHAa1336 | proQ | PSHAa1336 | PSHAa1679 | Homologs of previously reported genes of unknown function; membrane component. | Putative post-translational activator of ProP expression; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.773 |
| PSHAa1336 | rraB-2 | PSHAa1336 | PSHAa2583 | Homologs of previously reported genes of unknown function; membrane component. | Conserved protein of unknown function; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.774 |
| PSHAa1336 | rseA | PSHAa1336 | PSHAa0727 | Homologs of previously reported genes of unknown function; membrane component. | Putative anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), wh [...] | 0.744 |
| PSHAa1336 | yihI | PSHAa1336 | PSHAa2751 | Homologs of previously reported genes of unknown function; membrane component. | Conserved protein of unknown function; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.788 |
| PSHAa1819 | PSHAa1021 | PSHAa1819 | PSHAa1021 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family. | 0.754 |
| PSHAa1819 | PSHAa1336 | PSHAa1819 | PSHAa1336 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function; membrane component. | 0.765 |
| PSHAa1819 | lptC | PSHAa1819 | PSHAa2548 | Homologs of previously reported genes of unknown function. | Conserved protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.739 |
| PSHAa1819 | nlpI | PSHAa1819 | PSHAa1002 | Homologs of previously reported genes of unknown function. | Lipoprotein probably involved in cell division after interaction with a protease; May be involved in cell division. | 0.768 |