Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa2586Putative L-sorbosone dehydrogenase (SNDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (364 aa)    
Predicted Functional Partners:
parC
DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
  
    0.862
parE
DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.819
PSHAa2588
Homologs of previously reported genes of unknown function; enzyme.
     
 0.803
cpdA
Cyclic 3',5'-adenosine monophosphate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.801
PSHAa2590
Homologs of previously reported genes of unknown function.
       0.798
nudF
ADP-ribose pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.702
rraB-2
Conserved protein of unknown function; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
       0.526
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
       0.526
tolC
Outer membrane protein tolC precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.419
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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