Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PSHAa2607Homologs of previously reported genes of unknown function. (147 aa)    
Predicted Functional Partners:
rdgB
Putative inosine/xanthosine triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.899
PSHAa2606
Putative integral membrane resistance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter.
       0.787
proC
Pyrroline-5-carboxylate reductase (NAD(P)-binding); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.779
yggW
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.779
PSHAa2604
Conserved protein of unknown function; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.763
PSHAa1906
Homologs of previously reported genes of unknown function.
  
     0.699
PSHAa2610
Homologs of previously reported genes of unknown function.
       0.698
pilT
Twitching motility protein PilT (type IV pili); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.692
PSHAa1848
Putative cytochrome oxidase maturation protein, cbb3-type (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
     0.681
pilU
Twitching motility protein PilU (type IV pili); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.613
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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