Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa26192-hydroxyacid dehydrogenase family protein; Function of strongly homologous gene; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)    
Predicted Functional Partners:
PSHAa2153
Putative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
0.924
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.917
aceA
Isocitrate lyase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.910
PSHAb0379
Putative protein with predicted kinase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 0.910
eda
Multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.905
PSHAa1744
Putative 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
  0.905
gph
Phosphoglycolate phosphatase, contains a phosphatase-like domain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.903
PSHAa1814
Putative phosphoglycolate phosphatase, contains a phosphatase-like domain; Function of strongly homologous gene; enzyme.
    
  0.902
serC
3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
   
 
 0.544
pgm
Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
   0.513
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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