Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apaHDiadenosine tetraphosphatase (Ap4A hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (272 aa)    
Predicted Functional Partners:
apaG
Conserved protein (part of complex ksgA operon); Function of strongly homologous gene; 2157025.
  
  
 0.966
surA
Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
 
 
 0.921
ksgA
S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase, Kasugamycin dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.910
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase,(4-(phosphohydroxy)-L-threonine dehydrogenase); Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
     
 0.895
PSHAa2902
Homologs of previously reported genes of unknown function; 11347268, 14672542.
   
 0.877
PSHAa0443
Putative RNAse with metallo-beta-lactamase-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
 0.859
PSHAb0333
Putative protein phosphatase with Diacylglycerol kinase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
    
 
 0.777
imp
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
    0.759
trkH
Potassium transport protein, requires TrkE (Trk family); Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
  
 
 0.741
PSHAa2631
Homologs of previously reported genes of unknown function.
 
    0.711
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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