Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dfpBifunctional: 4'-phosphopantothenoylcysteine decarboxylase (N); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (397 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase (PPAT) (Dephospho-CoA pyrophosphorylase); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
 
 0.965
coaX
Putative transcriptional regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
 
  
 0.933
ttk
Putative transcriptional regulator of dUTPase (TetR/AcrR family); Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
 
    0.916
mazG
Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme.
  
  
  0.915
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
  
 0.902
PSHAa2467
Homologs of previously reported genes of unknown function.
     
  0.900
cysK
O-acetylserine sulfhydrylase, PLP-dependent enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.820
metK
Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   0.804
metC
Cystathionine beta-lyase, PLP-dependent (beta-cystathionase); Function of strongly homologous gene; enzyme.
   
 
  0.803
aspC
Aspartate aminotransferase (Transaminase A) (ASPAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.801
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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