| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cgtA | rluD | PSHAa2654 | PSHAa0933 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.913 |
| cgtA | rplA | PSHAa2654 | PSHAa0219 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.902 |
| cgtA | rplO | PSHAa2654 | PSHAa2811 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.895 |
| cgtA | rplQ | PSHAa2654 | PSHAa2805 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structural protein. | 0.896 |
| cgtA | rplS | PSHAa2654 | PSHAa0947 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.929 |
| cgtA | rplT | PSHAa2654 | PSHAa1399 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L20, also posttranslational autoregulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.958 |
| cgtA | rplU | PSHAa2654 | PSHAa2656 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.980 |
| cgtA | rpmA | PSHAa2654 | PSHAa2655 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structural protein; Belongs to the bacterial ribosomal protein bL27 family. | 0.995 |
| cgtA | rpmI | PSHAa2654 | PSHAa1398 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein A; Function of strongly homologous gene; structural protein; Belongs to the bacterial ribosomal protein bL35 family. | 0.896 |
| cgtA | rsfS | PSHAa2654 | PSHAa1027 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.907 |
| rluD | cgtA | PSHAa0933 | PSHAa2654 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.913 |
| rluD | rplO | PSHAa0933 | PSHAa2811 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.633 |
| rluD | rplQ | PSHAa0933 | PSHAa2805 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structural protein. | 0.635 |
| rluD | rplS | PSHAa0933 | PSHAa0947 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.721 |
| rluD | rplT | PSHAa0933 | PSHAa1399 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L20, also posttranslational autoregulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.749 |
| rluD | rplU | PSHAa0933 | PSHAa2656 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.704 |
| rluD | rpmA | PSHAa0933 | PSHAa2655 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structural protein; Belongs to the bacterial ribosomal protein bL27 family. | 0.627 |
| rluD | rsfS | PSHAa0933 | PSHAa1027 | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.646 |
| rplA | cgtA | PSHAa0219 | PSHAa2654 | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.902 |
| rplA | rplO | PSHAa0219 | PSHAa2811 | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.997 |
