Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbpA | clpB | PSHAa2878 | PSHAa0935 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.720 |
| cbpA | grpE | PSHAa2878 | PSHAa1222 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.903 |
| cbpA | hscA | PSHAa2878 | PSHAa2667 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.937 |
| cbpA | htpG | PSHAa2878 | PSHAa1207 | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.891 |
| clpB | cbpA | PSHAa0935 | PSHAa2878 | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | 0.720 |
| clpB | dnaJ | PSHAa0935 | PSHAb0358 | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...] | 0.861 |
| clpB | grpE | PSHAa0935 | PSHAa1222 | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.904 |
| clpB | hscA | PSHAa0935 | PSHAa2667 | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.906 |
| clpB | htpG | PSHAa0935 | PSHAa1207 | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.850 |
| dnaJ | clpB | PSHAb0358 | PSHAa0935 | Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...] | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.861 |
| dnaJ | grpE | PSHAb0358 | PSHAa1222 | Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...] | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | 0.979 |
| dnaJ | hscA | PSHAb0358 | PSHAa2667 | Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...] | Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.989 |
| dnaJ | htpG | PSHAb0358 | PSHAa1207 | Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...] | Chaperone protein htpG; Molecular chaperone. Has ATPase activity. | 0.964 |
| fdx | hscA | PSHAa2666 | PSHAa2667 | [2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.990 |
| fdx | hscB | PSHAa2666 | PSHAa2668 | [2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Co-chaperone protein Hsc20, involved in assembly of Fe-S clusters (specific for IscU); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.994 |
| fdx | iscA | PSHAa2666 | PSHAa2669 | [2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.977 |
| fdx | iscS | PSHAa2666 | PSHAa2671 | [2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Cysteine desulfurase (tRNA sulfurtransferase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.970 |
| fdx | iscU | PSHAa2666 | PSHAa2670 | [2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Fe-S assembly protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.994 |
| grpE | cbpA | PSHAa1222 | PSHAa2878 | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone. | 0.903 |
| grpE | clpB | PSHAa1222 | PSHAa0935 | Hsp 24 DnaK nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several [...] | ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.904 |
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