STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
damDNA adenine methylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (285 aa)    
Predicted Functional Partners:
aroB
Dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
  
 0.860
aroK
Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
    0.803
dusA
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
      
 0.786
mutH
Methyl-directed mismatch repair protein with restriction endonuclease-like domain; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
 
   
 0.783
metJ
Transcriptional repressor for methionine biosynthesis (MetJ family); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
  
     0.697
PSHAa2713
Homologs of previously reported genes of unknown function; membrane component.
  
  
 0.696
PSHAa1021
Homologs of previously reported genes of unknown function; Belongs to the UPF0250 family.
 
     0.626
gph
Phosphoglycolate phosphatase, contains a phosphatase-like domain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.604
pilQ
Putative type IV pilus biogenesis protein PilQ (cytoplasmic ATPase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.586
pilO
Putative Type IV pilus biogenesis protein PilO; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; structural protein.
     
 0.574
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (30%) [HD]