Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hutHHistidine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (548 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase (Urocanase, imidazolonepropionate hydrolase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
Imidazolonepropionase (imidazolone-5-propionate hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.984
hisD
Bifunctional HisD: L-histidinal:NAD+ dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.927
PSHAb0401
Histidine ammonia-lyase (hutT-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
  
 
0.923
PSHAa1438
Homologs of previously reported genes of unknown function.
     
  0.900
hutC
Histidine utilization repressor (GntR family); Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.897
hutG
Formiminoglutamate hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the arginase family.
  
  
 0.795
PSHAa0460
Putative orphan protein; Doubtful CDS.
  
  
 0.665
gcvP
Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.590
PSHAa1171
Homologs of previously reported genes of unknown function.
  
  
 0.558
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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