| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa2748 | cgtA | PSHAa2748 | PSHAa2654 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.643 |
| PSHAa2748 | pmbA | PSHAa2748 | PSHAa2747 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | Putative enzyme for maturation of Microcin B17 and degradation of CcdA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.763 |
| PSHAa2748 | rluD | PSHAa2748 | PSHAa0933 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.843 |
| PSHAa2748 | rplC | PSHAa2748 | PSHAa0144 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.619 |
| PSHAa2748 | rplD | PSHAa2748 | PSHAa0145 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.619 |
| PSHAa2748 | rplM | PSHAa2748 | PSHAa2532 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.626 |
| PSHAa2748 | rplU | PSHAa2748 | PSHAa2656 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.632 |
| PSHAa2748 | rpmF | PSHAa2748 | PSHAa1811 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial ribosomal protein bL32 family. | 0.630 |
| PSHAa2748 | rpmG | PSHAa2748 | PSHAa2641 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 50S ribosomal subunit protein L33; Function of homologous gene experimentally demonstrated in an other organism; structural protein; Belongs to the bacterial ribosomal protein bL33 family. | 0.838 |
| PSHAa2748 | rsfS | PSHAa2748 | PSHAa1027 | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.628 |
| cgtA | PSHAa2748 | PSHAa2654 | PSHAa2748 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 0.643 |
| cgtA | rluD | PSHAa2654 | PSHAa0933 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Pseudouridine synthase (pseudouridines 1911, 1915, 1917 in 23S RNA); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.913 |
| cgtA | rplC | PSHAa2654 | PSHAa0144 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.870 |
| cgtA | rplD | PSHAa2654 | PSHAa0145 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.870 |
| cgtA | rplM | PSHAa2654 | PSHAa2532 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.882 |
| cgtA | rplU | PSHAa2654 | PSHAa2656 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.980 |
| cgtA | rpmF | PSHAa2654 | PSHAa1811 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial ribosomal protein bL32 family. | 0.887 |
| cgtA | rpmG | PSHAa2654 | PSHAa2641 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L33; Function of homologous gene experimentally demonstrated in an other organism; structural protein; Belongs to the bacterial ribosomal protein bL33 family. | 0.865 |
| cgtA | rsfS | PSHAa2654 | PSHAa1027 | GTPase (Obg family) involved in ribosome maturation; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.907 |
| pmbA | PSHAa2748 | PSHAa2747 | PSHAa2748 | Putative enzyme for maturation of Microcin B17 and degradation of CcdA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative transport protein (ABC superfamily, ATP-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter; Belongs to the UPF0307 family. | 0.763 |