Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa2750Homologs of previously reported genes of unknown function. (171 aa)    
Predicted Functional Partners:
yihI
Conserved protein of unknown function; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
 
     0.947
ccmD
Heme exporter protein D (Cytochrome c-type biogenesis protein ccmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
  
     0.683
PSHAa1844
Putative Cbb3-type cytochrome oxidase, subunit 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
  
     0.671
lptC
Conserved protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.662
bamC
Putative lipoprotein-34 NlpB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.655
PSHAa1819
Homologs of previously reported genes of unknown function.
  
     0.649
PSHAa1848
Putative cytochrome oxidase maturation protein, cbb3-type (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
     0.633
PSHAa0240
Putative general secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.627
PSHAa2234
Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
  
     0.614
PSHAa0242
Putative general secretion pathway protein N; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
  
     0.611
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: medium (42%) [HD]