Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chlDPutative anion transport protein (ABC superfamily, ATP-binding protein); Function of strongly homologous gene; transporter. (469 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.774
PSHAb0458
Putative cyclopropane-fatty-acyl-phospholipid synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.576
gltB
Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.512
PSHAa2779
Putative fatty acid cis/trans isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.480
PSHAa2780
Putative orphan protein; No homology to any previously reported sequences.
       0.480
PSHAa0642
Putative orphan protein; No homology to any previously reported sequences.
 
     0.471
PSHAa1752
Homologs of previously reported genes of unknown function.
 
     0.412
PSHAa2569
Homologs of previously reported genes of unknown function; regulator.
  
     0.407
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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