node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | PSHAa1200 | PSHAa2790 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.967 |
apt | gsk | PSHAa1200 | PSHAa2334 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.938 |
apt | guaA | PSHAa1200 | PSHAa0649 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.996 |
gmk | apt | PSHAa2790 | PSHAa1200 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.967 |
gmk | gsk | PSHAa2790 | PSHAa2334 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.911 |
gmk | guaA | PSHAa2790 | PSHAa0649 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.964 |
gmk | ndk | PSHAa2790 | PSHAb0142 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.930 |
gmk | nrdA | PSHAa2790 | PSHAa1418 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.916 |
gmk | nrdB | PSHAa2790 | PSHAa1417 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 1, beta subunit; Function of strongly homologous gene; enzyme. | 0.907 |
gmk | pykA | PSHAa2790 | PSHAa1406 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.921 |
gmk | rpoZ | PSHAa2790 | PSHAa2791 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.986 |
gmk | spoT | PSHAa2790 | PSHAa2793 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Bifunctional: (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.966 |
gmk | yicC | PSHAa2790 | PSHAa2789 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Homologs of previously reported genes of unknown function. | 0.906 |
gsk | apt | PSHAa2334 | PSHAa1200 | Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.938 |
gsk | gmk | PSHAa2334 | PSHAa2790 | Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.911 |
gsk | guaA | PSHAa2334 | PSHAa0649 | Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.940 |
guaA | apt | PSHAa0649 | PSHAa1200 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.996 |
guaA | gmk | PSHAa0649 | PSHAa2790 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.964 |
guaA | gsk | PSHAa0649 | PSHAa2334 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Inosine-guanosine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.940 |
guaA | ndk | PSHAa0649 | PSHAb0142 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.537 |