node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gmk | ndk | PSHAa2790 | PSHAb0142 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.930 |
gmk | nrdA | PSHAa2790 | PSHAa1418 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.916 |
gmk | nrdB | PSHAa2790 | PSHAa1417 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 1, beta subunit; Function of strongly homologous gene; enzyme. | 0.907 |
gmk | pykA | PSHAa2790 | PSHAa1406 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.921 |
gmk | spoT | PSHAa2790 | PSHAa2793 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Bifunctional: (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.966 |
gppA | relA | PSHAa0115 | PSHAa0739 | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.919 |
gppA | spoT | PSHAa0115 | PSHAa2793 | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Bifunctional: (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.919 |
mazG | ndk | PSHAa0740 | PSHAb0142 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
mazG | nrdA | PSHAa0740 | PSHAa1418 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.623 |
mazG | nrdB | PSHAa0740 | PSHAa1417 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Ribonucleoside-diphosphate reductase 1, beta subunit; Function of strongly homologous gene; enzyme. | 0.568 |
mazG | pykA | PSHAa0740 | PSHAa1406 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.900 |
mazG | relA | PSHAa0740 | PSHAa0739 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.993 |
mazG | spoT | PSHAa0740 | PSHAa2793 | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | Bifunctional: (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
ndk | gmk | PSHAb0142 | PSHAa2790 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.930 |
ndk | mazG | PSHAb0142 | PSHAa0740 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme. | 0.900 |
ndk | nrdA | PSHAb0142 | PSHAa1418 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.922 |
ndk | nrdB | PSHAb0142 | PSHAa1417 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase 1, beta subunit; Function of strongly homologous gene; enzyme. | 0.916 |
ndk | pykA | PSHAb0142 | PSHAa1406 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.908 |
ndk | relA | PSHAb0142 | PSHAa0739 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.913 |
ndk | rplK | PSHAb0142 | PSHAa0218 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.823 |