Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa2836Homologs of previously reported genes of unknown function. (114 aa)    
Predicted Functional Partners:
PSHAa2835
Homologs of previously reported genes of unknown function.
  
  
 0.862
PSHAa2834
Transcriptional regulator, ArsR family; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.746
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS) (MECDP-synthase); Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
  
    0.591
PSHAa2832
Putative multidrug efflux system (AcrA/AcrE family); Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.589
PSHAa2833
Putative cation efflux system (AcrB/AcrD/AcrF family); Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.589
ybeY
Conserved protein of unknown function; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.443
sodB
Iron superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.440
PSHAa1138
Putative enzyme of the cysteine desulfurase family, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 0.439
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (22%) [HD]