Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
envZTwo-component system, OmpR family, osmolarity sensor histidine kinase EnvZ; Function of homologous gene experimentally demonstrated in an other organism; receptor. (433 aa)    
Predicted Functional Partners:
ompR
Two-component system, OmpR family, phosphate regulon response regulator OmpR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 0.997
PSHAa0654
Homologs of previously reported genes of unknown function.
 
 
0.914
arcA
Aerobic respiration control protein arcA (Dye resistance protein); Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.826
PSHAa2621
Putative Sensory box sensor histidine kinase/response regulator; Function of strongly homologous gene; receptor.
 
 
0.824
PSHAa0861
Putative transcriptional regulatory protein RstA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; regulator.
 
 
 0.818
cpxR
Transcriptional regulatory protein CpxR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.814
rstA
Response regulator (activator) in two-component regulatory; Function of strongly homologous gene; regulator.
 
 
 0.809
phoB
Phosphate regulon transcriptional regulatory protein phoB; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.791
cusR
Two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.779
greB
Transcription elongation factor and transcript cleavage; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.
     
 0.775
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: medium (48%) [HD]