Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PSHAa2877Homologs of previously reported genes of unknown function. (106 aa)    
Predicted Functional Partners:
cbpA
Curved DNA-binding protein, co-chaperone of DnaK (Hsp40 family); Function of strongly homologous gene; molecular chaperone.
 
 
 0.991
endA
Endonuclease I Precursor (Endo I); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.523
PSHAa0654
Homologs of previously reported genes of unknown function.
   
 
 0.502
dnaJ
Chaperone protein dnaJ (Heat shock protein J) (HSP40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]
  
 
 0.499
PSHAa1502
Homologs of previously reported genes of unknown function.
  
     0.497
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.449
PSHAa0110
Putative DnaJ-class molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; molecular chaperone.
  
 
 0.447
PSHAb0017
Putative Glutathione S-transferase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
     0.435
PSHAa2621
Putative Sensory box sensor histidine kinase/response regulator; Function of strongly homologous gene; receptor.
   
 
 0.431
PSHAa2876
Putative orphan protein; No homology to any previously reported sequences.
       0.422
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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