STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmpNitric oxide dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the globin family. (393 aa)    
Predicted Functional Partners:
PSHAa2881
Putative integral inner membrane permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
  
  
 0.957
norR
Transcriptional regulator of anaerobic NO reduction and detoxification (EBP family); Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.833
PSHAa2882
Putative orphan protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
       0.830
PSHAa2419
Homologs of previously reported genes of unknown function.
 
   
 0.751
PSHAa2451
Homologs of previously reported genes of unknown function.
  
  
 0.677
PSHAa1477
Probable nitrite reductase (EC 1.7.99.3); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the multicopper oxidase family.
 
  
 0.604
cysG
Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
       0.586
fre
NAD(P)H-flavin reductase; Function of strongly homologous gene; enzyme.
 
   
 0.545
cysI
Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
   
 0.523
PSHAa0654
Homologs of previously reported genes of unknown function.
  
  
 0.488
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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