Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fkpAPutative periplasmic peptidyl-prolyl cis-trans isomerase; Function of strongly homologous gene; enzyme. (250 aa)    
Predicted Functional Partners:
skp
Periplasmic molecular chaperone for outer membrane proteins; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.796
PSHAa2902
Homologs of previously reported genes of unknown function; 11347268, 14672542.
  
   0.770
slyX
Homologs of previously reported genes of unknown function; Belongs to the SlyX family.
     
 0.744
osmY
Putative hyperosmotically inducible periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
      
 0.670
ecfK
Putative outer membrane protein assembly factor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.654
surA
Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
   
 
 0.653
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
   
 0.634
ecfD
Putative lipoprotein with tetratricopeptide repeats (TPR) domain; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.604
apaH
Diadenosine tetraphosphatase (Ap4A hydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.587
infA
Protein chain initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.576
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.