Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slyXHomologs of previously reported genes of unknown function; Belongs to the SlyX family. (71 aa)    
Predicted Functional Partners:
PSHAa2902
Homologs of previously reported genes of unknown function; 11347268, 14672542.
       0.868
fkpA
Putative periplasmic peptidyl-prolyl cis-trans isomerase; Function of strongly homologous gene; enzyme.
     
 0.744
PSHAa2385
Putative HIT family hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
    0.596
ilvM
Acetolactate synthase II, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.574
PSHAa1638
Homologs of previously reported genes of unknown function.
  
     0.549
PSHAa2535
Homologs of previously reported genes of unknown function.
  
     0.488
PSHAa0988
Homologs of previously reported genes of unknown function.
  
     0.481
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
     0.457
yihI
Conserved protein of unknown function; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.435
rseA
Putative anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), wh [...]
  
     0.433
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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