Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSHAa2915Putative cold-active aminopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (613 aa)    
Predicted Functional Partners:
coaX
Putative transcriptional regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
       0.757
birA
Biotin-[protein] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
       0.757
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.757
PSHAa2383
Putative orphan protein; No homology to any previously reported sequences.
  
   0.660
PSHAa2386
Dipeptidyl peptidase IV; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
     0.550
miaA
Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
    
 0.545
PSHAa0187
Homologs of previously reported genes of unknown function.
  
     0.541
PSHAb0473
Homologs of previously reported genes of unknown function.
  
    0.501
PSHAa1628
Putative Glutamate carboxypeptidase II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
 
 
 0.483
PSHAb0474
Homologs of previously reported genes of unknown function.
  
    0.481
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.