Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PSHAa2951Homologs of previously reported genes of unknown function. (178 aa)    
Predicted Functional Partners:
parC
DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.918
PSHAa1310
Putative signal peptidase I family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the peptidase S26 family.
   
    0.898
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.893
PSHAa2952
Homologs of previously reported genes of unknown function.
       0.837
rmf
Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.
   
    0.836
phoU
Transcriptional repressor for high-affinity phosphate uptake; Plays a role in the regulation of phosphate uptake.
   
    0.833
lolB
Putative Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
    0.676
gltB
Glutamate synthase, large subunit, GOGAT; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.576
lepB
Signal peptidase I (SPase I) (Leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family.
   
    0.562
helD
Putative helicase IV; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
   
    0.551
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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